According to various reports, RB Curtis Martin, who's currently on the PUP list, will not play this season and most likely will never play again at all.
Martin, who has rushed for 14,101 yards in his career, was injured last season in Week 2, but played in 12 games before ending his year. He underwent surgery in December and was placed on the PUP list before training camp, so he could continue to rehabilitate the knee.